All-or-none (~100 mV) voltage spike propagating along axon: Na+ influx (depolarisation) → K+ efflux (repolarisation) → hyperpolarisation → return. Conducts at 1-100 m/s depending on myelination/diameter.
Action potential
Related concepts
- Voltage-gated ion channel
- Hodgkin-Huxley model
- Cardiac cycle
- Sensory transduction
- Excitation-contraction coupling
- Hill muscle model
- Cortical microcircuit
- Hubel-Wiesel (1962)
- Place cells (O'Keefe 1971)
- Buzsáki theta-γ (1989)
- fMRI (Ogawa 1990)
- Optogenetics (Deisseroth 2005)
- C. elegans connectome (1986)
- Hebb (1949)
- Cajal (1906)
- fMRI (Ogawa 1990)
- DMN (Raichle 2001)
- Predictive coding (Rao-Ballard 1999)
- Global workspace (Baars 1988)
- Classical conditioning (Pavlov 1903)