Microbial 7-alpha-dehydroxylation converts primary to secondary bile acids; secondary bile acids signal through FXR/TGR5 and regulate host glucose, lipid, immune homeostasis.
Microbial 7-alpha-dehydroxylation converts primary to secondary bile acids; secondary bile acids signal through FXR/TGR5 and regulate host glucose, lipid, immune homeostasis.