Broadly neutralising antibody (bNAb)

Layer 3 — Biologyin the Vaccinology subtree

bNAbs neutralise diverse viral strains by targeting conserved epitopes (HIV-CD4-binding-site / V3-loop / MPER / fusion-peptide; influenza HA-stem; coronavirus RBD-class-1/4). Lineage tracing via NGS-Ig-repertoire (Adams-Schief 2018). …