Levi 1997-2010: 5-FU, oxaliplatin, irinotecan show 2 to 5x toxicity differences and improved tumor response when delivered at specific circadian windows; trial outcomes mixed.
Levi 1997-2010: 5-FU, oxaliplatin, irinotecan show 2 to 5x toxicity differences and improved tumor response when delivered at specific circadian windows; trial outcomes mixed.