CDK bistable switch (Tyson-Novak)

Layer 3 — Biologyin the Cell Cycle subtree

Cyclin-CDK regulatory network exhibits hysteretic bistability via positive feedback (Cdc25 activation, Wee1 inactivation) generating saddle-node bifurcations; Tyson-Novak ODE model reproduces irreversible G2/M transition and oscillation in…