Cheng & Prusoff (1973) derived the closed-form relation between the experimentally-measured IC50 of a competitive enzyme inhibitor (the inhibitor concentration producing 50% inhibition of a fixed-substrate assay) and the true thermodynamic…
Cheng & Prusoff (1973) derived the closed-form relation between the experimentally-measured IC50 of a competitive enzyme inhibitor (the inhibitor concentration producing 50% inhibition of a fixed-substrate assay) and the true thermodynamic…