Click chemistry (Sharpless-Meldal-Bertozzi)

Layer 2 — Chemistryin the chemical-biology subtree

Sharpless-Meldal 2001 + Bertozzi 2003 bioorthogonal: Cu(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition; Bertozzi strain-promoted (SPAAC); Nobel Chem 2022.

Related concepts

Ordinary differential equation (ODE)
Arrhenius slope: d(ln k)/d(1/T) = −E_a/k_B (exact)

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