Saliva-cortisol peak ~30 min after waking (CAR cortisol-awakening-response) + nadir ~midnight; HPA-axis controlled; modulated by light + stress; chronopharmacological target for adrenal-insufficiency + Cushing.
Saliva-cortisol peak ~30 min after waking (CAR cortisol-awakening-response) + nadir ~midnight; HPA-axis controlled; modulated by light + stress; chronopharmacological target for adrenal-insufficiency + Cushing.