Kuhn 1942 / Stephenson 1972: loop-of-Henle multiplies single-step transverse osmotic gradient into axial cortico-medullary gradient ~1200 mOsm/kg via active NaCl transport in thick ascending limb. Modelled as coupled ODEs for tubular flow…
Kuhn 1942 / Stephenson 1972: loop-of-Henle multiplies single-step transverse osmotic gradient into axial cortico-medullary gradient ~1200 mOsm/kg via active NaCl transport in thick ascending limb. Modelled as coupled ODEs for tubular flow…