CRISPR base editing (Liu 2016)

Layer 2 — Chemistryin the chemical-biology subtree

Komor-Liu 2016 cytidine-base editor (CBE) C->T; Gaudelli-Liu 2017 adenine-base editor (ABE) A->G; nick + deaminase fusion to dCas9; therapeutic-grade beam-201 trial 2024.

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Tree (graph-theoretic)

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