DNA melting (Poland-Scheraga 1966)

Layer 2 — Chemistryin the biophysical-chemistry subtree

Poland-Scheraga 1966 helix-coil transition: cooperative melting of dsDNA; sequence-dependent Tm = sum_dinuc deltaG/deltaS; basis of UV-melting + qPCR design.

Related concepts

Ordinary differential equation (ODE)
Boltzmann entropy formula

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