First-order elimination: C(t)=C₀·e^(−kt); t½ = ln(2)/k

Layer 3 — Biologyin the neuropharmacology subtree

First-order elimination is the foundational pharmacokinetic model for most therapeutic drugs at therapeutic concentrations: the plasma concentration follows dC/dt = −k·C, solution C(t) = C₀·exp(−k·t). Defining feature: the elimination…

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