Folate one-carbon metabolism

Layer 3 — Biologyin the Amino Acid And Nucleotide Metabolism subtree

Tetrahydrofolate (THF) carries one-carbon units (methyl, methylene, formyl) for thymidylate, purine, and methionine synthesis. Vitamin-B9 dependent; target of methotrexate, sulfonamides.

Related concepts

Cytosine (C)
Hallmark: deregulating cellular energetics

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