α-cell-secreted 29-aa peptide hormone binding hepatic glucagon receptor (GPCR → Gs → cAMP). Stimulates glycogenolysis + gluconeogenesis, opposing insulin. Secreted during fasting.
α-cell-secreted 29-aa peptide hormone binding hepatic glucagon receptor (GPCR → Gs → cAMP). Stimulates glycogenolysis + gluconeogenesis, opposing insulin. Secreted during fasting.