G-protein-coupled receptor activation triggers GDP→GTP exchange on Gα subunit, Gα-GTP dissociates from Gβγ, modulates downstream effectors (adenylyl cyclase, PLC-β, ion channels) producing second messengers (cAMP, IP₃/DAG, Ca²⁺) that…
G-protein-coupled receptor activation triggers GDP→GTP exchange on Gα subunit, Gα-GTP dissociates from Gβγ, modulates downstream effectors (adenylyl cyclase, PLC-β, ion channels) producing second messengers (cAMP, IP₃/DAG, Ca²⁺) that…