Nascent tumors are edited by the immune system in three phases (elimination → equilibrium → escape) — Schreiber's cancer immunoediting. Escape mechanisms: MHC-I downregulation (hides from CD8+ T cells); upregulation of inhibitory ligands…
Nascent tumors are edited by the immune system in three phases (elimination → equilibrium → escape) — Schreiber's cancer immunoediting. Escape mechanisms: MHC-I downregulation (hides from CD8+ T cells); upregulation of inhibitory ligands…