Hanahan 2022: heritable changes in tumor-cell state achieved through chromatin remodeling rather than DNA mutation. Evidenced by SWI/SNF and polycomb complex subunit alterations in ~20% of cancers (ARID1A, SMARCA4, EZH2), by tumor…
Hanahan 2022: heritable changes in tumor-cell state achieved through chromatin remodeling rather than DNA mutation. Evidenced by SWI/SNF and polycomb complex subunit alterations in ~20% of cancers (ARID1A, SMARCA4, EZH2), by tumor…