Perutz 1963 (Nobel 1962) Hb 4 subunits T<->R quaternary transition; Hill coefficient n=2.8; Bohr effect H+/CO2 pK_R<pK_T allosteric coupling; basis of modern allostery theory.
Perutz 1963 (Nobel 1962) Hb 4 subunits T<->R quaternary transition; Hill coefficient n=2.8; Bohr effect H+/CO2 pK_R<pK_T allosteric coupling; basis of modern allostery theory.