Homologous recombination (Rad51-BRCA)

Layer 3 — Biologyin the Dna Repair And Recombination subtree

Petes-Stahl 1979 + Rothstein 1983 HR: MRN complex + CtIP resect; RPA + BRCA2-Rad51 strand-exchange; D-loop + Holliday-junction; BRCA1/2 tumor-suppressors; PARP-inhibitor synthetic-lethality.

Related concepts

Tree (graph-theoretic)
Watson-Crick base pairing

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