GnRH pulse-generator (arcuate KNDy neurons) drives ~hourly LH/FSH pulses; modelled as relaxation oscillator with kisspeptin-NKB excitation and dynorphin inhibition. Hopf bifurcation in feedback gain switches between tonic and pulsatile…
GnRH pulse-generator (arcuate KNDy neurons) drives ~hourly LH/FSH pulses; modelled as relaxation oscillator with kisspeptin-NKB excitation and dynorphin inhibition. Hopf bifurcation in feedback gain switches between tonic and pulsatile…