DNA polymerases extend only 5'→3'; consequence at a replication fork: leading strand is synthesised continuously toward the fork; lagging strand is synthesised in short Okazaki fragments (1-2 kb in eukaryotes, 100-200 nt prokaryotic) using…
DNA polymerases extend only 5'→3'; consequence at a replication fork: leading strand is synthesised continuously toward the fork; lagging strand is synthesised in short Okazaki fragments (1-2 kb in eukaryotes, 100-200 nt prokaryotic) using…