Leloup-Goldbeter mammalian molecular-clock model (Per/Cry/Bmal feedback)

Layer 3 — Biologyin the chronobiology subtree

Leloup-Goldbeter mammalian-clock model (Leloup-Goldbeter 2003 *PNAS* 100, 7051; refined 2004 *J Theor Biol* 230, 541) is the canonical 16-19-variable ODE description of the mammalian transcription-translation feedback loop: BMAL1-CLOCK…

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Goodwin: dx/dt=a_g/(K^n+z^n)−b_g·x; symmetric SS s·(s^n+1)=1; n=1: s=(√5−1)/2 (golden)

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