Limb bud (AER + ZPA, Shh + FGF)

Layer 3 — Biologyin the Developmental Biology subtree

Saunders 1948 AER + ZPA: apical-ectodermal-ridge FGF8 maintains progress-zone proximodistal; zone-of-polarizing-activity Shh anteroposterior; cross-talk +/- BMP feedback loops.

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