LLPS in neurodegeneration (TDP-43 / FUS)

Layer 3 — Biologyin the Neurodegenerative Disease subtree

Molliex 2015 / Patel 2015: stress-granule LLPS of TDP-43 / FUS / hnRNPA1 transitions to aberrant solid-state aggregates over time; ALS-mutations accelerate the maturation; new therapeutic-target class.

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