Mass spectrometry proteomics

Layer 3 — Biologyin the Structural Biology Methods subtree

Peptide identification + quantification by MS/MS. Bottom-up (tryptic digest) most common. Workflows: LC-MS/MS → database search (Mascot, MaxQuant) → FDR control. Enables proteome-wide profiling.

Related concepts

Phosphorylation
Chemical proteomics
Hydrogen-deuterium exchange MS

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