Plasma-membrane lipid-asymmetry framework

Layer 3 — Biologyin the Lipid Metabolism subtree

Plasma membrane outer leaflet enriched in PC and SM; inner leaflet in PE and PS. Asymmetry maintained by ATP-dependent flippases (P4-ATPases) and scramblases (TMEM16F). Loss of asymmetry (PS exposure) is canonical apoptotic signal:…

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