MutS/MutL → MSH2/MSH6 + MLH1/PMS2 in eukaryotes: post-replicative recognition of base-pair mismatches and small (1-3 nt) insertion/deletion loops; nick-directed strand-discrimination identifies the daughter strand; exonuclease EXO1 excises…
MutS/MutL → MSH2/MSH6 + MLH1/PMS2 in eukaryotes: post-replicative recognition of base-pair mismatches and small (1-3 nt) insertion/deletion loops; nick-directed strand-discrimination identifies the daughter strand; exonuclease EXO1 excises…