Mismatch repair (Modrich)

Layer 3 — Biologyin the Dna Repair And Recombination subtree

Modrich 1980s (Nobel 2015) MMR: MutS_alpha/_beta detect mismatch; MutL_alpha endonuclease nicks newly-synthesized strand; EXO1 excision + Pol-delta resynthesis; Lynch-syndrome MSH2/MLH1 link.

Related concepts

Tree (graph-theoretic)
Watson-Crick base pairing

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