mRNA vaccine platform (Karikó-Weissman)

Layer 3 — Biologyin the Vaccinology subtree

Karikó-Weissman 2005 pseudouridine-modified mRNA escapes innate-immune detection; Pardi-Hou-Karikó-Weissman 2017 LNP-mRNA platform. COVID-19 BNT162b2 (Pfizer-BioNTech) + mRNA-1273 (Moderna) deployed under EUA Dec 2020. >10 billion doses…