Sensing of tissue-damaging stimuli. Free nerve endings with TRPV1 (heat, capsaicin), TRPA1 (chemical irritant), ASIC (acid), Piezo2 (mechanical). Distinct from subjective 'pain' (requires cortical processing).
Sensing of tissue-damaging stimuli. Free nerve endings with TRPV1 (heat, capsaicin), TRPA1 (chemical irritant), ASIC (acid), Piezo2 (mechanical). Distinct from subjective 'pain' (requires cortical processing).