O2-hemoglobin dissociation curve

Layer 3 — Biologyin the Cardiovascular And Respiratory subtree

Sigmoidal saturation vs pO2 reflecting cooperative O2 binding (Hill coefficient ~2.8). Right-shifted by ↓pH (Bohr effect), ↑T, ↑2,3-BPG, ↑CO2. Facilitates tissue unloading.

Related concepts

Pulmonary gas exchange
Bohr effect
Hemoglobin cooperativity: Hill equation Y = L^n / (K^n + L^n); n ≈ 2.8

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