Dixit-Parnas-Adamson-Regev 2016 / CROP-seq Datlinger 2017: pool of CRISPR-perturbed cells → scRNA-seq with sgRNA capture. Reads out functional consequences of 100s-1000s of gene knockouts in parallel. Enables genotype→phenotype mapping…
Dixit-Parnas-Adamson-Regev 2016 / CROP-seq Datlinger 2017: pool of CRISPR-perturbed cells → scRNA-seq with sgRNA capture. Reads out functional consequences of 100s-1000s of gene knockouts in parallel. Enables genotype→phenotype mapping…