Phosphofructokinase-1 (PFK-1)

Layer 3 — Biologyin the Glycolysis And Gluconeogenesis subtree

Committed step of glycolysis: F6P + ATP → F1,6-BP + ADP. Major regulatory enzyme: allosterically activated by AMP, F2,6-BP; inhibited by ATP, citrate, H+.

Related concepts

Glycolysis (Embden-Meyerhof-Parnas)
Allosteric regulation

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