Purine de-novo biosynthesis (IMP pathway) framework

Layer 3 — Biologyin the Amino Acid And Nucleotide Metabolism subtree

10-step pathway from PRPP (5-phospho-ribose-1-pyrophosphate) → IMP using glycine, glutamine, aspartate, formate (via N⁵,N¹⁰-methylene-tetrahydrofolate), and CO₂. Branches at IMP into AMP and GMP. Allosterically controlled by AMP, GMP…

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