Pyrrolysine (Pyl, O) — 22nd amino acid

Layer 3 — Biologyin the Biochemistry Foundations subtree

Co-translationally inserted at UAG by dedicated tRNA^Pyl + PylRS, without an accessory element. Found in methanogenic archaea (Methanosarcinaceae); the PylRS/tRNA^Pyl pair underpins much unnatural-amino-acid incorporation in genetic-code…

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