Pyruvate kinase

Layer 3 — Biologyin the Glycolysis And Gluconeogenesis subtree

Glycolytic step 10: PEP + ADP → pyruvate + ATP (substrate-level phosphorylation). Allosterically activated by F1,6-BP (feed-forward); inhibited by ATP, alanine; PKM2 in cancer.

Related concepts

Explore Pyruvate kinase on the interactive knowledge graph →