Universal ribozyme decoding mRNA and catalysing peptide-bond formation. Bacterial 70S = 30S + 50S; eukaryotic 80S = 40S + 60S. Peptidyl transferase centre is rRNA-catalysed.
Ribosome
Related concepts
- Translation
- Translation initiation
- Peptide-bond formation
- RNA world hypothesis
- Translation elongation
- Adaptor hypothesis (Crick 1957)
- Ribosome (Yonath 2009)
- Wobble (Crick 1966)
- EF-Tu (Jurnak 1985)
- IRES (Pelletier-Sonenberg 1988)
- NMD (Leeds 1991)
- XPA-G (Cleaver 1968)
- BRCA1 (King 1990)
- Recombination (Meselson-Radding 1975)
- DSBR (Szostak 1983)
- MMR (Modrich 2015)
- CRISPR-Cas9 (Doudna 2012)
- Repressilator (Elowitz 2000)
- Synthetic Mycoplasma (Venter 2010)
- CRISPR (Zhang 2013)