Single-cell ATAC-seq (Buenrostro)

Layer 3 — Biologyin the Single-Cell Biology subtree

Buenrostro-Wu-Litzenburger 2015 / 10x Multiome 2020: Tn5 transposase tags accessible chromatin in single cells. Reveals cis-regulatory landscape per cell-type. Joint scRNA + scATAC (10x Multiome / SHARE-seq) maps regulator → target. …

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