Dorsal lip of amphibian blastopore that induces secondary body axis when transplanted (Spemann-Mangold 1924). Secretes BMP antagonists (Chordin, Noggin, Follistatin) + Wnt antagonists (Dkk, Frzb).
Dorsal lip of amphibian blastopore that induces secondary body axis when transplanted (Spemann-Mangold 1924). Secretes BMP antagonists (Chordin, Noggin, Follistatin) + Wnt antagonists (Dkk, Frzb).