Strategic-bond ranking: ring > stereocenter > C-heteroatom

Layer 2 — Chemistryin the retrosynthesis-strategy subtree

Strategic-bond identification (Corey-Long-Rubenstein Science 1985; LHASA computer-assisted retrosynthesis) ranks candidate disconnections by their simplification potential. Highest priority: ring-forming bonds (Diels-Alder constructs two…

Related concepts

Strategic-bond count = k-1 on k-stereocenter linear chain

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