Translesion synthesis (Y-family pols)

Layer 3 — Biologyin the Dna Repair And Recombination subtree

Friedberg 1990s + Goodman 2002 TLS: damage-tolerance via Y-family polymerases (eta/iota/kappa/Rev1) low-fidelity bypass; eta bypasses CPD; ubiquitinated PCNA recruits Y-pol.

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