Inhibitor binds only the ES complex (not free E). Vmax and apparent K_M decrease in the same ratio. Lineweaver-Burk lines are parallel. Classic example: lithium on inositol monophosphatase.
Inhibitor binds only the ES complex (not free E). Vmax and apparent K_M decrease in the same ratio. Lineweaver-Burk lines are parallel. Classic example: lithium on inositol monophosphatase.