Urea cycle

Layer 3 — Biologyin the Amino Acid And Nucleotide Metabolism subtree

Five-step hepatic cycle converting toxic ammonia + aspartate → urea (ureotelic nitrogen excretion). Split between mitochondria (CPS1, OTC) and cytosol (ASS, ASL, arginase).

Related concepts

Transamination
Ammonia detoxification

Explore Urea cycle on the interactive knowledge graph →