X-chromosome inactivation

Layer 3 — Biologyin the Epigenetics And Chromatin subtree

Dosage-compensation mechanism in female mammals: one of two X chromosomes randomly silenced per cell via XIST lncRNA-mediated spreading of heterochromatin (PRC2, macroH2A, DNA methylation).

Related concepts

Epigenetics
Long non-coding RNA (lncRNA)

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