Zinc finger (Klug 1985 TFIIIA)

Layer 2 — Chemistryin the bioinorganic-chemistry subtree

Klug 1985 (Nobel 1982 EM-related) zinc-finger Cys2His2 fold; ~30 aa coordinates Zn2+; foundation of sequence-specific DNA recognition + designer-protein engineering (Pabo + Carroll).

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Tree (graph-theoretic)

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