Amyloid-PET imaging (PiB / florbetapir)

Layer 3 — Biologyin the Neurodegenerative Disease subtree

Klunk 2004 Pittsburgh-Compound-B (PiB) thioflavin-derivative binds A-beta plaques in vivo; FDA-approved florbetapir (Avid 2012) / flutemetamol / florbetaben; defines AD biomarker A in NIA-AA framework.

Related concepts

Matrix and determinant
Braak staging (PD / AD progression)

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