Braak staging (PD / AD progression)

Layer 3 — Biologyin the Neurodegenerative Disease subtree

Braak-Braak 1991-2003: histopathological staging of AD (NFT distribution stages I-VI) + PD (alpha-synuclein Lewy-pathology stages 1-6 starting in olfactory + brainstem); supports trans-synaptic spread hypothesis.

Related concepts

Tree (graph-theoretic)
Amyloid-PET imaging (PiB / florbetapir)

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