Caspase-3 activation network (Eissing 2004 / Bagci 2006 ODE) exhibits bistability between live and apoptotic states via positive feedback loops involving caspase-9, IAPs, and Bax/Bcl-2. Saddle-node bifurcation in stress parameter sets the…
Caspase-3 activation network (Eissing 2004 / Bagci 2006 ODE) exhibits bistability between live and apoptotic states via positive feedback loops involving caspase-9, IAPs, and Bax/Bcl-2. Saddle-node bifurcation in stress parameter sets the…