Base editor

Layer 3 — Biologyin the Synthetic Biology subtree

Liu lab 2016/2017: Cas9-nickase fused to cytidine or adenine deaminase enables C→T (CBE) or A→G (ABE) single-base edits without DSB. Expands therapeutic CRISPR scope to point mutations.

Related concepts

CRISPR-Cas9
Prime editing

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