Allosteric feedback regulation of PFK-1 framework

Layer 3 — Biologyin the Glycolysis And Gluconeogenesis subtree

Phosphofructokinase-1 (PFK-1) is the canonical glycolytic flux-control point. Inhibited by ATP and citrate (energy/intermediate-rich states). Activated by AMP and fructose-2,6-bisphosphate (PFK-2 product, hormonally regulated by glucagon…

Related concepts

Hill v = V·Sⁿ/(Kⁿ+Sⁿ): n is the log-log slope at S = K

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